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In patients with suspected ET who lack JAK2 and MPL mutations, the exclusion of reactive causes is particularly important ().In studies of。

ET usually develops very slowly. It can affect people of any age. But it usually affects middle aged and older people. The average age at diagnosis is about 65 years although it can affect children and young adults.

Overview: Essential thrombocythemia is a Janus kinase 2 (JAK2) mutation-prevalent myeloproliferative neoplasm characterized by clonal thrombocytosis; clinical course is often。

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